Colistin is a bactericidal polypeptide antibiotic belongs to polymyxin group. It produces its antibacterial effect by interacting strongly with phospholipids in bacterial cell membrane & radically disturbed their permeability & function . Colistin is active against G -ve bacteria including E. coli & Salmonella spp.

Each 100 gm contains: Colistin sulphate ………………………………………… 20.75 gm (Eq. to Colistin base 16.6 gm = 500 MIU)

Calves, broiler chickens & laying hens.

It is used for the treatment of :It is used for the treatment of :• Colibacillosis caused by E – coli susceptible to colistin.• Salmonellosis caused by Salmonella spp. susceptible to colistin.

Route of administration: orally via drinking water. For active ingredient: Calves: 3.4 mg of colistin base / kg b. wt. every 12 hours. Broiler chickens & laying hens: 4.1 mg of colistin base / kg b. wt. per day. For whole product: Calves: 205 mg of the product / 10 kg b. wt. every 12 hours for 3 days. (Eq. to 125 gm of the product / 1000 liter drinking water). Broiler chickens & laying hens: 24.6 mg of the product / kg b. wt. per day for 3 days. (Eq. to 125 gm of the product / 1000 liter drinking water).

The medicated water should be prepared daily.

• Not to be used in animal hypersensitive to colistin.

• Not to be used in animal hypersensitive to colistin.

• Not to be used in animals with renal failure.

• Not to be used with cations (calcium, magnesium & manganese) and unsaturated fatty acids as colistin antagonized with them. 

No side effects in the recommended dose but in case of overdose digestive problems may occur such as a transient softening of feces or bloat.

Meat: Calves: 2 days. Broiler chickens: 2 days. Eggs: Laying hen: 0 days

In dry place at temp. not exceed 30 C° to be used immediately after opening.