Royalneo 21

Properties:
Neomycin: is an aminoglycoside bactericidal antibiotic that its antimicrobial action results from the fixation of the 30 subunit of ribosomes. Also disturbs the bacterial membrane permeability. Neomycin: active against gram (-)negative and gram (+)positive bacteria, such as Escherichia coli, Staphylococcus aureus, Klebsiella pneumoniae, Streptococcus faecalis, Haemophilus influenzae, Mycobacterium tuberculosis , Proteus vulgaris ,Bacillus anthracis, Salmonella spp. And Shigella spp.
Composition:
Each 1gm contains: Neomycin Sulphate ………………………………………………300 mg (Equivalent to Neomycin base 210 mg)
Target species:
Broiler Chickens
Indications:
Broiler Chickens:
Royalneo21%: used for treatment of diarrhea associated with salmonellosis that caused by Salmonella spp.
Royalneo21%: reduce mortalities associated with Colibacillosis caused by Escherichia coli and the diarrhea caused by any of the susceptible organisms that mentioned above.
Dosage & Route of administration:
Route of administration: :Orally. For whole product: 0.05gm Royalneo21% / kg body weight for 3-5 days. 0.5gm Royalneo21% / liter of drinking water for 3-5 days.
Warning& Precaution:
• Administer in a good quantity of water to consume the dose completely.
• Administer in a good quantity of water to consume the dose completely.
• Prepare the medicated water daily.
• Do not administer with neuromuscular blockers, general anesthetics, anti diuretics or other aminoglycosides.
Contra – Indication:
• Do not administer to dehydrated animals with renal failure or with respiratory depression.
• Do not administer to dehydrated animals with renal failure or with respiratory depression.
• Do not administer to birds with a history of hypersensitivity to the antibiotic.
Side Effects:
• The prolonged use can cause malabsorption syndrome & intestinal dysbacteriosis.
• The prolonged use can cause malabsorption syndrome & intestinal dysbacteriosis.
• At high dose and prolonged use can cause nephrotoxic and ototoxic effect.
• Neomycin is particularly toxic to the auditory and renal system.
• Aminoglycosides may impair neuromuscular transmission if used peri-operatively in association with anesthesia.
Withdrawal time:
Broiler Chickens: 5 days
Storage:
Stored at temperature not exceeding 30ْ c, in dry place, away from light, and to be used immediately after opening and Reconstituting