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Liquiprolium

Properties:

Amprolium hydrochloride is 1-[(4-amino-2-propyl-5-pyrimidinyl)methyl]-2-methylpyridinum chloride.

 It is a coccidiostat which is used for the treatment and prevention of coccidiosis in chickens, including laying hens, and turkeys.

The antiparasitic activity of Amprolium is thought to be related to competitive inhibition of active thiamine transport into the parasite, and interferes with the metabolism of glucides necessaries for coccidian multiplication and survival.

There is fifty fold greater sensitivity of the parasite system compared with the host system.

Amprolium act on the first generation schizonts to prevent the merozoite production and has some activity against sexual stages and the sporulated oocyst.

Composition:

Each one ml contains: 250 mg Amprolium.

Eq. to 282.74 mg Amprolium hydrochloride

Target species:

Chickens (broilers, pullets, layers, breeder hens) and Turkeys.

Indications:

Treatment of coccidiosis in Chicken that caused by E.tenella, E.necatrix, E.acervulina, E.maxima and E.brunetti.

Treatment of coccidiosis in Turkey that caused E.adenoides, E.gallapavonis and E.meleagrimitis.

Dosage & Route of administration:

Route of administration: Orally via drinking water.

For whole product:

Chickens (broilers, pullets, layers, breeder hens) and Turkeys:

0.8 ml Liquiprolium / liter of drinking water, per day for 5-7 consecutive days.

Warning& Precaution:

Medicated drinking water should be replaced every 24 hours.

Sufficient access to the system of water supply should be available for the animals to be treated to ensure adequate water consumption

Contra – Indication:

Do not use water rich in calcium ions.

Liquiprolium MUST NOT be given together with Vitamin B.

Side Effects:

Prolonged uses can produce thiamine deficiencies

When symptoms appear, thiamine must be administered.

Withdrawal time:

Chickens (broilers, pullets, layers, breeder hens) and Turkeys:

Meat: 5 days.

Egg: 5 days.

Storage:

Stored at temperature not exceed 30 C˚.