Tylosin is a macrolide antibiotic produced by a strain of Streptomyces fradiae. It exerts its antimicrobial effect by inhibiting protein synthesis of susceptible micro-organisms. The Tylosin spectrum of activity includes amongst others Gram-positive bacteria, some Gram – negative strains such as Pasteurella, and Mycoplasma spp. In most species peak plasma concentrations have been attained 1 to 2 hours after administration of tylosin. Compared to plasma levels clearly higher tissue concentrations have been observed. Tylosin was extensively metabolised.
Each 1.10 gm contains……………………………….1.10 gm Tylosin tartrate. Equivalent to 1 gm Tylosin base.
Broiler chickens and Turkeys.
Broiler Chickens: Treatment of chronic respiratory diseases (CRD) caused by Mycoplasma gallisepticum and Mycoplasma synoviae . Turkeys: Treatment of infectious sinusitis caused by Mycoplasma gallisepticum
Dosage & Route of administration:
Route of administration: :orally via drinking water.Route of administration: :orally via drinking water.For whole product:Turkeys: 0.55-0.825 gm Taylor / litre per drinking water for 3-5 days.Broiler Chickens:• For the treatment of chronic respiratory disease:0.55-0.825 gm Taylor / litre per drinking water for 3-5 days.• For the treatment of necrotic enteritis: 0.44 gm Taylor / liter per day for 3 days.
Do not use in horses.
Do not use in animals with hepatic disorders.
Contra – Indication:
Do not use in cases of known resistance to Tylosin or cross-resistance to other macrolide (MLS-resistance). Do not use in animals vaccinated with Tylosin-sensitive vaccines either at the same time or within 1 week previously.
There is no evidence of Tylosin toxicity in chickens, turkeys, or calves when administered orally at up to three times the recommended dose.
Turkeys (meat and offal): 2 days Broiler Chickens (meat and offal): 1 day
Stored at temperature not exceed 30 C˚.