Tylvalosin is a macrolide antibiotic. Macrolide are metabolites or derivatives of metabolites of soil organisms obtained by fermentation. They interfere with protein synthesis by reversibly binding to the 50S ribosome subunit. They are generally considered bacteriostatic.
Tylvalosin has activity against pathogenic organisms isolated from a range of animal species mainly Gram-positive organisms and mycoplasma but also some Gram-negative organisms. Tylvalosin has activity against Mycoplasma gallisepticum in chickens.
Macrolide (including Tylvalosin) have been shown to have effects on the innate immune
system, which may augment the direct effects of the antibiotic on the pathogen and aid the clinical situation.
Each 1gram contains: 972.35 mg. Tylvalosin tartrate ( Eq. to 850 mg Tylvalosin base.)
Treatment of respiratory disease associated with Mycoplasma gallisepticum in broiler chickens.
Dosage & Route of administration:
Route of administration: orally via drinking water.
For active ingredient:
200-250 mg Tylvalosin / liter of drinking water for 3-5 days.
20-25 mg Tylvalosin / kg of body weight. For 3-5 days.
For whole product :
23.5 – 29.4 gm Royaltvalosin85% / 1000 kg body weight. For 3-5 days.
1 gm Royaltvalosin85% / 3.4 – 4.2 liters of drinking water. For 3-5 days.
- The product may be mixed directly into the drinking water system or first mixed as a stock solution into a smaller amount of water, which is then added into the drinking water system.
Contra – Indication:
Not authorized for use in laying birds producing eggs for human consumption. Do not use within 14 days of onset of the laying.
No signs of intolerance have been observed in chickens at up to 150 mg Tylvalosin per kg bodyweight per day for 5 days
Meat and offal: 5 days.
Stored at temperature not exceed 30 C˚.
White plastic (HDPE) container closed with white plastic (HDPE) cap outer label of 100,150, 250 gm. & 500 gm.